- Extracellular protein is the protein that is destined for export from a cell such asdigestive enzyme that is made by pancreas cell.
- The organelles that involved in the process are nucleus, ribosome, RER, Golgi apparatus and mitochondria.
- Flow chart shows how the internal membrane system of a cell packages a protein for export.
1. Instructions for making protein are transcribed from DNA by RNA in the nucleus.
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2. RNA leaves the nucleus through nuclear pore and proceeds to a ribosome located on theRER.
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3. Ribosome synthesis the correct sequence of amino acids for synthesizing that particular protein as instructed.
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4. When protein synthesis is complete, the protein travels through the RER and is then encapsulated in a transport vesicle.
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5. The transport vesicle fuses with a Golgi apparatus, releasing the protein.
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6. In the Golgi apparatus, the protein is further modified and is then shunted to the ends of Golgi apparatus or cisternae. There, the protein waits for a secretory vesicle.
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7. The secretory vesicle will carry the protein to the plasma membrane of the cell and fuses with it.
Then the protein is released outside the cell
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2. RNA leaves the nucleus through nuclear pore and proceeds to a ribosome located on theRER.
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3. Ribosome synthesis the correct sequence of amino acids for synthesizing that particular protein as instructed.
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4. When protein synthesis is complete, the protein travels through the RER and is then encapsulated in a transport vesicle.
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5. The transport vesicle fuses with a Golgi apparatus, releasing the protein.
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6. In the Golgi apparatus, the protein is further modified and is then shunted to the ends of Golgi apparatus or cisternae. There, the protein waits for a secretory vesicle.
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7. The secretory vesicle will carry the protein to the plasma membrane of the cell and fuses with it.
Then the protein is released outside the cell
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